Virtual School Text-to-Speech

To enable spoken content. Navigate to Settings on the iPad, then Accessibility, Spoken Content, Speak Selection and Speak Screen need toggled on (green is on). To have the content read, swipe down with two fingers. A speech-to-text controller can be enabled to have on the screen as well. Toggle the Speech Controller to on for a small control to appear on the screen.
A short, 3-minute Apple video shows the process

On a Macbook, use the directions below from Apple. 
  1. On your Mac, choose Apple menu  > System Preferences, click Accessibility, then click Speech.

  2. Select the “Speak selected text when the key is pressed” checkbox. By default, speaking is enabled when you press Option-Esc. To choose a different key, click Change Key, press one or more modifier keys (Command, Shift, Option, or Control) together with another key, then click OK.

  3. To have your Mac start speaking, press the specified key. To stop the speaking, press the key again. If text is selected when you press the key, the selected text is spoken. Otherwise, available text items in the current  window are spoken.